Nora is shown to be a Caucasian woman with pale white skin, long white hair, light blue eyes, and blue lipstick. Her attire is shown to be a blue headband, a long blue dress, and low blue heels (although later on, she is seen barefoot).
Nora ran a mom-and-pop cryogenics lab when she met Victor Fries who was the CEO of a multinational corporation tasked with crushing all competitors, including her lab. However, they met online and fell in love before he realized that she was the same person he was competing with. They married, but soon Nora fell ill with a rare blood disease that threatened to kill her. With no other option, Victor Fries froze her in a block of ice to halt the progress of the disease, and then set out to find a cure.
After capturing and freezing Harley Quinn and her crew, Mister Freeze explains that he is planning to use Harley as a human subject to test his cure for Nora. To save herself, Harley informs him that her friend Poison Ivy is a "genius biochemist" and could possibly find a cure for her.
After seeing Nora frozen in ice and observing Freeze's strange behavior, Harley assumes that he froze Nora after she tried to leave him and then made up her disease as an excuse to justify it. Harley then defrosts her body and breaks Freeze's gun, only to learn that Nora was dying and Freeze was telling the truth.
Ivy finds a solution to cure Nora, at the cost of Freeze's life, who sacrificed himself to cure her via blood transfusion. Before he dies, he implores his wife to go on and enjoy her life. He reaches out to his wife but weakens and fades just before he can touch her. Crying for her husband, she screams at Harley and her crew to leave.
- ❝ I've never been to an all female island before, seems like it'll be great for crying! ❞
- — Nora Fries
Harley invites her to Ivy's bachelorette party at Themyscira, in which she assumes was only a pity invite because she killed her husband, or he "killed himself" as Harley considers it. At Hedonikka she is seen making out with Maxie Zeus (much to Catwoman's horror). She alongside the rest of the Cobb Squad helps take down Eris and save Queen Hippolyta. When they returned to Gotham, she has sex with Zeus again in a car before taking her home.
"Something Borrowed, Something Green"
Eat. Bang! Kill. Tour
- "Journey to Love" (cameo; pictured)
- Like her 1992 incarnation, Nora was diagnosed with a terminal illness, and Mister Freeze attempt to find a cure for her.
- According to Mister Freeze, Nora own a cryogenics lab, inherited from her parents and they met online.
- This is the only iteration of the character to have a character arc outside of her relationship with her husband.
- Unlike most incarnations of Nora Fries, this version of the character hooks up with Maxie Zeus due to being a character in Harley Quinn's self parody show.
- "Thawing Hearts" DC Universe (April 24, 2020)