Additionally, she has voiced several minor characters on the show:
- James Gordon's wife Barbara
- Police officer Cheryl
- Multiple students in the episode "Riddler U"
- A singing fish in the episode "Bachelorette".
Before Harley Quinn, she has starred in various television series, including roles such as Sally Heep in Boston Legal (2004–2006), Laura Daughtery in Surface (2005–2006), Rachel Chapman in How to Make It in America (2010–2011), and Dr. Cat Black Childrens Hospital (2008–2016), and in films, including roles such as Ashley in Over Her Dead Body (2008), Tipper in What Happens in Vegas (2008), Agness Adler in It's Complicated (2009), Lucy in No Strings Attached (2011), Brenda Paauwe Bernstein in Million Dollar Arm (2014), Annie Dwyer in No Escape (2015), Chloe in The Secret Life of Pets (2016), and Zoey Bell in Home Again (2017). Other examples of her acting roles are Vanessa Fisk in Spider-Man: Into the Spider-Verse (2018), Ariel and Black Widow in Robot Chicken (2012), and Katrina Peanutbutter in BoJack Horseman (2015-2018).